P07814 | SYEP_HUMAN | Bifunctional glutamate/proline--tRNA ligase (EPRS1)

3D structures mapped by conservation among orthologs

[ Domain: "Glutathione S-transferase (GST)-C" // GST_C_3 ]

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[ Domain: "Class II aaRS and biotin synthetases" // tRNA-synt_2b ]

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[ Domain: "C-terminal domain of ProRS" // ProRS-C_1 ]

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[ Domain: "S15/NS1 RNA-binding domain" // WHEP-TRS ]

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[ Domain: "Anticodon-binding domain of Class II aaRS" // HGTP_anticodon ]

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[ Domain: pdbs with more than 2 multi-domains ]

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[ Alpha Fold Model ] (go)

Known binders annotated in ChEMBL

Ki table

molecule_chembl_id	structure	assay_type	relation	values	units	mol_wt	smiles	organism	assay_chembl_id	bao_label
CHEMBL357355		Ki	=	15.0	nM	376.64	Cc1cc(Cl)cc2c(C(=O)O)cc(-c3ccc(Br)cc3)nc12	Homo sapiens	CHEMBL844882	single protein format